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Friday, June 25, 2010

SIZE GENETIC: YOUR SOLUTION TO PEYRONIE

Banana Type of erection – problems of Sexual Intercourse

You may think you are the only guy to have a ‘banana’ shaped penis, but you are not alone.

According to leading urologists 388 men out of 100,000 suffer from penile curvatures, so the next time you go to the gym and feel self-conscious, don’t worry. They have been there too.
But here is the great news… you don’t have to put up with this. Nor do you have to put your body through the trials of surgery and intra-penile steroid injections to put it right. At SizeGenetics we can help.
But first let us first show you: why it happens?
What causes a bent penis?
Commonly known as peyronie’s disease, penile curvature is a result of fibrous tissue developing on the tunica albugiena of the penis. And the end result? A lump or hard band of tissue focussed around the centre of your penis, with a 30% curvature when erect.
Peyronie’s is normally found in men aged between 40-70, but some men in their teens have been diagnosed with the condition.
And it is here where the problem begins. This slight curvature can make sex either uncomfortable, painful or in some cases even impossible.
You see, women may be built to accommodate for your penis size – 4-9 inches… it doesn’t matter. But their vaginas are not made to cope with curvatures.

You can change this.

At SizeGenetics we can offer you a unique type 1 medical device that is clinically proven to increase your penis length by 30% in as little 24 weeks, and at the same time correct penile angulations.
And all it takes for you to boost your penis size by 2.75 inches and enjoy the results… is 2-3 hours of your time every day.
And we think you will be impressed with the results. Not only will you and your partner be enjoying the best sex of your life, you will be able to experiment with new and exciting positions without having to worry about your penis.
Using our unique traction device, you can offer your body a natural cure for peyronie’s disease without the risk of impotency or deformation.
Plus, in no time you’ll be experiencing great and satisfying sex that will not only be pain free but fun too.
For just £226.11 you can also benefit from:

• Medical Type 1 device
• Comfort add-on and spare parts
• PenisHealth DVD and online access
• Real sex for real people online DVD
• Seductive Massage online DVD
• Online access to LoveCentria and 54+ DVD’s filled with a variety of tips and sexual positions, that will have your partner asking for more, more, more

And your penile curvature? Will be a thing of the past once you begin experimenting with our DVD range. Your partner will never know it ever even existed…
All she will be concerned with is the new bigger, thicker you.

Order your SizeGenetics device today.
Click on the link below to make your order now:
http://track.moreniche.com/hit.php?w=128563&s=24

Permenda LTD

Tuesday, June 1, 2010

Study: 10 minutes of exercise, hour-long effects

WASHINGTON – Ten minutes of brisk exercise triggers metabolic changes that last at least an hour. The unfair news for panting newbies: The more fit you are, the more benefits you just might be getting.

We all know that exercise and a good diet are important for health, protecting against heart disease and diabetes, among other conditions. But what exactly causes the health improvement from working up a sweat or from eating, say, more olive oil than saturated fat? And are some people biologically predisposed to get more benefit than others?

They're among questions that metabolic profiling, a new field called metabolomics, aims to answer in hopes of one day optimizing those benefits — or finding patterns that may signal risk for disease and new ways to treat it.

"We're only beginning to catalog the metabolic variability between people," says Dr. Robert Gerszten of Massachusetts General Hospital, whose team just took a step toward that goal.

The researchers measured biochemical changes in the blood of a variety of people: the healthy middle-aged, some who became short of breath with exertion, and marathon runners.

First, in 70 healthy people put on a treadmill, the team found more than 20 metabolites that change during exercise, naturally produced compounds involved in burning calories and fat and improving blood-sugar control. Some weren't known until now to be involved with exercise. Some revved up during exercise, like those involved in processing fat. Others involved with cellular stress decreased with exercise.

Those are pretty wonky findings, a first step in a complex field. But they back today's health advice that even brief bouts of activity are good.

"Ten minutes of exercise has at least an hour of effects on your body," says Gerszten, who found some of the metabolic changes that began after 10 minutes on the treadmill still were measurable 60 minutes after people cooled down.

Your heart rate rapidly drops back to normal when you quit moving, usually in 10 minutes or so. So finding lingering biochemical changes offers what Gerszten calls "tantalizing evidence" of how exercise may be building up longer-term benefits.

Back to the blood. Thinner people had greater increases in a metabolite named niacinamide, a nutrient byproduct that's involved in blood-sugar control, the team from Mass General and the Broad Institute of MIT and Harvard reported last week in the journal Science Translational Medicine.

Checking a metabolite of fat breakdown, the team found people who were more fit — as measured by oxygen intake during exercise — appeared to be burning more fat than the less fit, or than people with shortness of breath, a possible symptom of heart disease.

The extremely fit — 25 Boston Marathon runners — had ten-fold increases in that metabolite after the race. Still other differences in metabolites allowed the researchers to tell which runners had finished in under four hours and which weren't as speedy.

"We have a chemical snapshot of what the more fit person looks like. Now we have to see if making someone's metabolism look like that snapshot, whether or not that's going to improve their performance," says Gerszten, whose ultimate goal is better cardiac care.

Don't expect a pill ever to substitute for a workout — the new work shows how complicated the body's response to exercise is, says metabolomics researcher Dr. Debbie Muoio of Duke University Medical Center.

But scientists are hunting nutritional compounds that might help tweak metabolic processes in specific ways. For example, Muoio discovered the muscles of diabetic animals lack enough of a metabolite named carnitine, and that feeding them more improved their control of blood sugar. Now, Muoio is beginning a pilot study in 25 older adults with pre-diabetes to see if carnitine supplements might work similarly in people who lack enough.

WEIGHT LOSS

Weight loss is a reduction in body mass characterized by a loss of adpose tissues (body fat) and skeletal muscles.


DESCRIPTION
Unintentional weight loss is the most common symptom of cancer and often a side effect of cancer treatments. A poor response to cancer treatments, reduced quality of life, and shorter survival time may result from substantial weight loss. The body may become weaker and less able to tolerate cancer therapies. As body weight decreases, body functionality declines and may lead to malnutrition, illness, infection, and perhaps death.

Most cancer patients in the United States expect to suffer weight loss during treatment for their disease; a study of 938 patients from 17 communities in upstate New York reported in 2004 that weight loss was the fourth most commonly expected side effect of cancer therapy, after fatigue, nausea, and sleep disturbances.

Severe malnutrition is typically defined in two ways: functionally (increased risk of morbidity and/or mortality) and by degree of weight loss (greater than 2% per week, 5% per month, 7.5% per 3 months, and 10% per 6 months). Without considering a specific time course, grading is as follows:

Grade 0 = less than 5.0% weight loss

Grade 1 = 5.0% to 9.9%

Grade 2 = 10.0% to 19.9%

Grade 3 = greater than 20.0%

Grade 4 (life-threatening) is not specifically defined. Paying attention to weight loss at an early stage is necessary to prevent deterioration of weight, body composition, and performance status.

CAUSES
There are many reasons for weight loss in cancer patients, including appetite loss because of the effect of cancer treatments (chemotherapy, radiation therapy, or biological therapy) or psychological factors such as depression. Patients may suffer from anorexia and lose desire to eat, and thus consume less energy. When inadequate calories are consumed, it can lead to "wasting" of body stores (muscle and adipose tissue). Weight loss may be temporary or may continue at a life-threatening pace.

Weight loss may be also be a consequence of an increased requirement for calories (energy) due to infection, fever, or the effects of the tumor or cancer treatments. If infection or fever is present, it is necessary to consider that there is an increased caloric need of approximately 10% to 13% per degree above 98.6°F (37°C). Therefore, energy intake has to be increased to account for this rise in body temperature.

Weight loss may be a result of a common problem in cancer called cahexia. Approximately half of all cancer patients experience cachexia, a wasting syndrome that induces metabolic changes leading to a loss of muscle and fat. It has been proposed that cachexia may be due to the effects of the tumor, but this is debatable considering some patients with very large tumors do not experience cachexia, while others do even though tumors are less than 0.01% of body mass. Cachexia is most common in patients with pancreatic and gastric cancer. Approximately 83% to 87% of these patients experience weight loss. Cachexia is characterized by such symptoms as decreased appetite, fatigue, and poor performance status. It can occur in individuals who consume enough food, but due to disease complications, cannot absorb enough nutrients (i.e. fat malabsorption). Although energy expenditure is sometimes increased, cachexia can occur even with normal energy expenditure. Cachexia is multifactorial in nature and associated with mechanical factors, psychological factors, changes in taste, and cytokines. It should be distinguished from anorexia, in which there is a loss of desire to eat, resulting in weight loss. Cachexia is a serious complication in cancer patients, thought to be responsible for as many as 20% of all deaths from cancer.

SPECIAL CONCERNS
In order to allow normal tissue repair following aggressive cancer therapies, patients require adequate calories and macronutrients in the form of protein, carbohydrates, and fat. Inadequate consumption of food and/or poor nutrition may impair the ability of a patient to tolerate a specific therapy. If a low tolerance to therapy necessitates a decrease in dose, the therapy's effectiveness could be compromised. Wound healing may also be impaired with poor nutrition and inadequate energy intake.

Research has demonstrated that men often experience significantly more weight loss than women over the course of the disease and lose weight much faster. On average, survival time for men is shorter than for women. Significant predictors of patient survival are stage of disease, initial weight-loss rate, and gender.

TREATMENTS
Nutritional problems related to side effects should be addressed to ensure adequate nutrition and prevent weight loss. In particular, cancer patients should maintain an adequate intake of calories and protein to prevent protein-calorie malnutrition. The patient's caloric requirements can be calculated by a dietitian or doctor since nutrient requirements vary considerably from patient to patient. Moreover, patient education about nutrition is vitally important; several recent studies have shown that almost half of all cancer patients in the United States receive no nutritional information from health care professionals, including the 18% who experience significant weight loss.

The following dietary tips may help patients to reduce weight loss:

Eat more when feeling the hungriest.

Eat foods that are enjoyed the most.

Eat several small meals and snacks instead of three large meals. A regular meal schedule should be kept so meals are not missed.

Have ready-to-eat snacks on hand such as cheese and crackers, granola bars, muffins, nuts and seeds, canned puddings, ice cream, yogurt, and hard boiled eggs.

Eat high-calorie foods and high-protein foods.

Take a small meal as to enjoy the satisfaction of finishing a meal. Have seconds if still hungry.

Eat in a pleasant atmosphere with family and friends if desired.

Make sure to consume at least eight to 10 glasses of water per day to maintain fluid balance.

Consider commercial liquid meal replacements such as Ensure, Boost, Carnation, and Sustacal.

An appetite stimulant may be given in order to prevent further weight loss such as megestrol acetate or dexamethasone. In clinical trials, both these medications appear to have similar and effective appetite stimulating effects with megestrol acetate having a slightly better toxicity profile. Fluoxymesterone has shown inferior efficacy and an unfavorable toxicity profile.

As of 2004, researchers at the Medical College of Virginia are studying a group of compounds known as cannabinoids for the treatment of cachexia and vomiting associated with cancer treatment. The best-known natural cannabinoids are derived from marijuana.

Further research is needed in order to devise an effective treatment for the loss of muscle tissue in cachexia. As of 2004, there are no medications, nutritional supplements, or other treatments that are even moderately successful in reversing the wasting of muscle tissue in cachexia.

ALTERNATIVE AND COMPLEMENTARY THERAPIES
Depression may affect approximately 15%–25% of cancer patients, particularly if the prognosis for recovery is poor. If anorexia is due to depression, there are antidepressant choices available through a physician. Counseling may be also be sought through a psychologist or psychiatrist to cope with depression.

It is important to check with a dietitian or doctor before taking nutritional supplements or alternative therapies because they may interfere with cancer medications or treatments. St. John's Wort has been used as a herbal remedy for treatment of depression, but it and prescription antidepressants is a dangerous combination that may cause symptoms such as nausea, weakness, and may cause one to become incoherent.

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